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腹膜后血管损伤的持续挑战。

The ongoing challenge of retroperitoneal vascular injuries.

作者信息

Coimbra R, Hoyt D, Winchell R, Simons R, Fortlage D, Garcia J

机构信息

Department of Surgery, University of California San Diego 92103-8896, USA.

出版信息

Am J Surg. 1996 Nov;172(5):541-4; discussion 545. doi: 10.1016/S0002-9610(96)00231-0.

Abstract

BACKGROUND

Retroperitoneal vascular injury remains one of the most frequent causes of death following abdominal trauma. A risk analysis of the association between potential outcome predictors and mortality following abdominal aorta and inferior vena cava injuries was performed.

METHODS

Eighty-nine patients sustaining abdominal aortic or inferior vena cava injury were concurrently evaluated for a 10-year period and retrospectively reviewed. A multiple logistic regression model evaluated the following variables:presence of shock on admission, base deficit (< -10 or > or = -10), classification by the organ injury scale (OIS), blood transfusion, crystalloid infusion, total infusion volume, associated injuries, site of injury, and presence of retroperitoneal tamponade.

RESULTS

Overall mortality for all injuries was 57%. Excluding all death on arrival (DOA) patients, the mortality rate decreased to 45.7%. Death following abdominal aortic injuries was significantly associated with free bleeding in the peritoneal cavity, acidosis, and an injury in the suprarenal location (OIS > 4). For inferior vena cava injuries and combined abdominal aortic and inferior vena cava injuries, death was associated with free bleeding, the suprarenal location (OIS = 4), and the presence of shock on admission as well.

CONCLUSIONS

Despite advances in transport and resuscitation, mortality of aortic and vena cava injuries remains unchanged. Shock on admission, bleeding without retroperitoneal tamponade, acidosis, and the suprarenal location each play a significant role in mortality. Immediate identification associated with a rapid surgical approach are the only factors that may improve survival of such devastating injuries.

摘要

背景

腹膜后血管损伤仍然是腹部创伤后最常见的死亡原因之一。对腹主动脉和下腔静脉损伤后潜在结局预测因素与死亡率之间的关联进行了风险分析。

方法

对89例腹主动脉或下腔静脉损伤患者进行了为期10年的同期评估,并进行回顾性分析。多元逻辑回归模型评估了以下变量:入院时休克的存在、碱缺失(<-10或≥-10)、器官损伤评分(OIS)分类、输血、晶体液输注、总输注量、合并损伤、损伤部位以及腹膜后填塞的存在情况。

结果

所有损伤的总体死亡率为57%。排除所有入院即死亡(DOA)患者后,死亡率降至45.7%。腹主动脉损伤后的死亡与腹腔内自由出血、酸中毒以及肾上腺部位损伤(OIS>4)显著相关。对于下腔静脉损伤以及腹主动脉和下腔静脉联合损伤,死亡与自由出血、肾上腺部位(OIS=4)以及入院时休克的存在情况也相关。

结论

尽管在转运和复苏方面取得了进展,但主动脉和腔静脉损伤的死亡率仍未改变。入院时休克、无腹膜后填塞的出血、酸中毒以及肾上腺部位在死亡率中均起重要作用。立即识别并采取快速手术方法是可能提高此类严重损伤患者生存率的唯一因素。

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