Howell S J, Sear Y M, Yeates D, Goldacre M, Sear J W, Foëx P
Nuffield Department of Anaesthetics, John Radcliffe Hospital, Oxford.
Anaesthesia. 1996 Nov;51(11):1000-4. doi: 10.1111/j.1365-2044.1996.tb14990.x.
We performed a retrospective case-control study to investigate hypertension and admission blood pressure as risk factors for postoperative cardiovascular death. We identified records of 76 patients who had died of a cardiovascular cause within 30 days of anaesthesia and elective surgery and 76 matched controls. From the records of each patient (case and control) we recorded the admission blood pressure and details of any history of hypertension. A pre-operative history of hypertension was strongly associated with perioperative cardiovascular death (p < 0.001 with one degree of freedom: odds ratio 4.14, 95% confidence intervals 1.63-11.69). There was no association between systolic or diastolic pressure at admission for operation and perioperative cardiovascular death. The mean admission systolic pressure of the cases was 145.5 mmHg (range 90-250 mmHg) and that of the controls was 146.5 mmHg (range 100-200 mmHg). The mean admission diastolic pressure of the cases was 83.2 mmHg (range 60-130 mmHg), and that of the controls was 84.5 mmHg (range 60-110 mmHg).
我们进行了一项回顾性病例对照研究,以调查高血压和入院血压作为术后心血管死亡的危险因素。我们确定了76例在麻醉和择期手术后30天内死于心血管疾病的患者记录以及76例匹配的对照。从每位患者(病例和对照)的记录中,我们记录了入院血压和任何高血压病史的详细信息。术前高血压病史与围手术期心血管死亡密切相关(自由度为1时p<0.001:比值比4.14,95%置信区间1.63 - 11.69)。手术入院时的收缩压或舒张压与围手术期心血管死亡之间没有关联。病例组的平均入院收缩压为145.5 mmHg(范围90 - 250 mmHg),对照组为146.5 mmHg(范围100 - 200 mmHg)。病例组的平均入院舒张压为83.2 mmHg(范围60 - 130 mmHg),对照组为84.5 mmHg(范围60 - 110 mmHg)。