Reis B L, Evans G W
J Nutr. 1977 Sep;107(9):1683-6. doi: 10.1093/jn/107.9.1683.
A previous study resulted in the discovery of a unique, undesignated strain of mice, referred to as SM (Super Mouse), whose progeny exhibited a resistance to dietary zinc deficiency when pups from the strain suckled dams fed a zinc-deficient diet. Examination of the zinc metabolism in these mice demonstrated in the study reported here that SM mice accumulated significantly more zinc during in utero development than do mice of other strains. Adult mice of the SM strain contained significantly more bone zinc than did mice of other strains. Adult SM mice excreted significantly less 65Zn than did mice of other strains when the mice were fed a zinc-deficient diet. These observations suggest that SM mice are able to resist periods of zinc-deficiency as a result of the development of highly efficient systems for storing and reabsorbing zinc.
先前的一项研究发现了一种独特的、未命名的小鼠品系，称为SM（超级小鼠），当该品系的幼崽 suckled 食用缺锌饮食的母鼠时，其后代对饮食性锌缺乏具有抗性。在本研究报告中对这些小鼠的锌代谢进行的检查表明，与其他品系的小鼠相比，SM小鼠在子宫内发育期间积累的锌明显更多。SM品系的成年小鼠所含的骨锌比其他品系的小鼠明显更多。当给小鼠喂食缺锌饮食时，成年SM小鼠排泄的65Zn明显少于其他品系的小鼠。这些观察结果表明，由于开发了高效的锌储存和再吸收系统，SM小鼠能够抵抗锌缺乏期。
