Woolliscroft J, Barbosa J
J Nutr. 1977 Sep;107(9):1702-6. doi: 10.1093/jn/107.9.1702.
Carbohydrate tolerance was studied by intravenous glucose tolerance tests in normal and chromium deficient rats. A significant difference in glucose metabolism between chromium deficient and chromium supplemented rats was demonstrated only when the glucose decay constant was calculated from the line fitting the plotted logarithms of the excess plasma glucose concentrations. Calculation of the glucose decay constant from the line fitting the logarithms of the total plasma glucose concentrations showed no significant difference between the two groups. This finding suggests that either the first method is more sensitive to mild changes in intravenous glucose tolerance in the rat, or the observed difference is a methodological artifact.
通过对正常大鼠和缺铬大鼠进行静脉葡萄糖耐量试验来研究碳水化合物耐受性。仅当根据拟合血浆葡萄糖过量浓度对数图的直线计算葡萄糖衰减常数时，才证明缺铬大鼠和补充铬的大鼠之间在葡萄糖代谢方面存在显著差异。根据拟合总血浆葡萄糖浓度对数的直线计算葡萄糖衰减常数时，两组之间没有显著差异。这一发现表明，要么第一种方法对大鼠静脉葡萄糖耐量的轻微变化更敏感，要么观察到的差异是一种方法学假象。
