Balo K P, Segbena K, Mensah A, Mihluedo H, Bechetoille A
Service d'Ophtalmologie, CHU Tokoin, Lomé, Togo.
J Fr Ophtalmol. 1996;19(8-9):497-504.
There are few publications concerning retinal complications of hemoglobinopathies in our country. We studied recruited patients to evaluate these complications.
From October 1993 to August 1995, 66 patients were recruited among clinical hematology out patients; all of them underwent acetate electrophoretic diagnosis and fluorescein angiographic examination.
The mean age of the patients was 26,92 years, ranging from 5 years to 50 years; the genotypic forms were 34 SC (51.51%), 15 SS (22.72%), 11 AC (16.66%), 2 AS (3.03%), 2 CC (3.03%), and 2 A2F (3.03%). Thirty eight patients (57.57%) had retinopathies. The majority were proliferative retinopathies in 55,26% cases and in 44,73% non proliferarive retinopathies. These retinopathies were essentially present with SC (26 cases for 34 SC, 76.47%), predominantly proliferative forms (21 cases for 26 SC, 80.76%).
Retinal complications are common in Togolese sickle cell patients; clinical course usually leads to proliferations. Early screening could help improve prevention, including laser photocoagulation.
我国关于血红蛋白病视网膜并发症的文献较少。我们对招募的患者进行研究以评估这些并发症。
1993年10月至1995年8月，从临床血液科门诊患者中招募了66例患者；所有患者均接受了醋酸盐电泳诊断和荧光素血管造影检查。
患者的平均年龄为26.92岁，范围从5岁至50岁；基因型形式为34例SC型（51.51%）、15例SS型（22.72%）、11例AC型（16.66%）、2例AS型（3.03%）、2例CC型（3.03%）和2例A2F型（3.03%）。38例患者（57.57%）患有视网膜病变。大多数为增殖性视网膜病变，占55.26%，非增殖性视网膜病变占44.73%。这些视网膜病变主要见于SC型（34例SC型中有26例，占76.47%），主要为增殖性形式（26例SC型中有21例，占80.76%）。
多哥镰状细胞病患者中视网膜并发症很常见；临床病程通常会导致增殖。早期筛查有助于改善预防措施，包括激光光凝治疗。
