Rampen F H, Steijlen P M
Department of Dermatology, Sint Anna Hospital, Oss, The Netherlands.
Dermatology. 1996;193(3):236-8. doi: 10.1159/000246252.
Induction of delayed-type hypersensitivity has recently been introduced for resistant viral warts. The method is not painful and less destructive than most other modalities.
We assessed the efficacy of topical diphencyprone (diphenylcyclopropenone) treatment for recalcitrant warts.
From September 1988 to June 1995, 134 patients with periungual and/or palmoplantar warts were entered into the study. Eight weekly applications were delivered.
The scheduled treatment course and follow-up were completed by 111 patients. There were 49 complete and 18 partial remissions. The rate of positive responders (60%) compares with the results published by other authors.
Diphencyprone is an effective treatment for resistant warts, especially in palmoplantar and periungual locations.
迟发型超敏反应诱导法最近已被用于治疗顽固性病毒性疣。该方法无痛，且比大多数其他方法破坏性小。
我们评估了外用二苯环丙烯酮治疗顽固性疣的疗效。
1988年9月至1995年6月，134例患有甲周和/或掌跖疣的患者进入本研究。每周给药一次，共给药八次。
111例患者完成了预定的治疗疗程和随访。有49例完全缓解和18例部分缓解。阳性反应者的比例（60%）与其他作者发表的结果相当。
二苯环丙烯酮是治疗顽固性疣的有效方法，尤其适用于掌跖和甲周部位。
