King B M, Cook J T, Rossiter K N, Theobold L M, Sam H
Department of Psychology, University of New Orleans, LA 70148, USA.
Physiol Behav. 1996 Dec;60(6):1569-71. doi: 10.1016/s0031-9384(96)00318-6.
Bilateral lesions in the most posterodorsal aspects of the amygdala in female rats resulted in immediate and dramatic weight gains on a standard lab chow diet. The rate of weight gain returned to normal by Day 20, but the difference in body weight between animals with amygdaloid lesions and those with sham lesions was maintained for the duration of the study (60 days). Because rats with posterodorsal amygdaloid lesions have also been found to be hyperinsulinemic, it is hypothesized that the lesions result in a similar, though smaller, version of the syndrome that follows lesions of the ventromedial hypothalamus.
雌性大鼠杏仁核最背侧后部的双侧损伤导致其在标准实验室饲料喂养下体重立即显著增加。到第20天时体重增加速率恢复正常，但杏仁核损伤组动物与假损伤组动物之间的体重差异在研究期间（60天）一直存在。由于发现背侧后部杏仁核损伤的大鼠也存在高胰岛素血症，因此推测这些损伤导致了一种类似于腹内侧下丘脑损伤后出现的综合征，只是程度较轻。
