• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

波斯湾退伍军人国民警卫队单位中慢性胃肠道症状的高患病率。

High prevalence of chronic gastrointestinal symptoms in a National Guard Unit of Persian Gulf veterans.

作者信息

Sostek M B, Jackson S, Linevsky J K, Schimmel E M, Fincke B G

机构信息

Department of Medicine, Boston Veterans Affairs Medical Center, Boston University School of Medicine, Massachusetts, USA.

出版信息

Am J Gastroenterol. 1996 Dec;91(12):2494-7.

PMID:8946972
Abstract

OBJECTIVES

To determine the prevalence and spectrum of GI complaints in a group of Persian Gulf veterans (PGV) and to compare these data to a group of veterans (controls) from the same unit who were not deployed to the Persian Gulf region.

METHODS

A 68-item survey was distributed to 136 members of a single National Guard Unit. The survey asked the veterans to rate the frequency of GI symptoms before, during, and after the Persian Gulf war had concluded. The participants were also asked to rate frequency of 10 non-GI symptoms at the time of this survey.

RESULTS

Fifty-seven PGV and 44 nondeployed veterans participated in the survey. Before the Persian Gulf war, both PGV and control groups reported low frequencies of GI symptoms. A majority of the PGV experienced GI symptoms during their deployment to the Gulf region, which persisted after their return to the United States. There were many significant differences observed between the two groups in frequency of both GI and non-GI symptoms. The greatest differences seen were for excessive gas, loose or greater than three stools per day, incomplete rectal evacuation, and abdominal pain.

CONCLUSIONS

A high prevalence of chronic GI symptoms exists in this group of PGV and is significantly greater than a group of controls. The most prevalent chronic GI symptoms are those that have been associated with functional GI disorders. However, the abrupt onset and clustering in this group suggests that nonfunctional etiologies may be contributing factors.

摘要

目的

确定一组波斯湾退伍军人(PGV)胃肠道不适的患病率和症状谱,并将这些数据与同一部队中未部署到波斯湾地区的一组退伍军人(对照组)进行比较。

方法

向一个国民警卫队单位的136名成员发放了一份包含68个条目的调查问卷。该问卷要求退伍军人对波斯湾战争之前、期间和结束之后胃肠道症状的发生频率进行评分。同时,还要求参与者对本次调查时10种非胃肠道症状的发生频率进行评分。

结果

57名PGV和44名未部署的退伍军人参与了调查。在波斯湾战争之前,PGV组和对照组报告的胃肠道症状发生频率均较低。大多数PGV在部署到海湾地区期间出现了胃肠道症状,回国后这些症状仍然存在。两组在胃肠道和非胃肠道症状的发生频率上存在许多显著差异。观察到的最大差异在于肠胃胀气过多、每天大便稀溏或超过三次、直肠排空不完全以及腹痛。

结论

这组PGV中慢性胃肠道症状的患病率很高,且显著高于对照组。最常见的慢性胃肠道症状与功能性胃肠疾病有关。然而,该组症状的突然发作和聚集表明非功能性病因可能也是促成因素。

相似文献

1
High prevalence of chronic gastrointestinal symptoms in a National Guard Unit of Persian Gulf veterans.波斯湾退伍军人国民警卫队单位中慢性胃肠道症状的高患病率。
Am J Gastroenterol. 1996 Dec;91(12):2494-7.
2
State of health after deployment in the Persian Gulf. The Danish Gulf War Study.部署到波斯湾后的健康状况。丹麦海湾战争研究。
Dan Med Bull. 1999 Nov;46(5):416-9.
3
Risk factors for gastrointestinal symptoms. The Danish Gulf War Study.胃肠道症状的风险因素。丹麦海湾战争研究。
Dan Med Bull. 1999 Nov;46(5):420-3.
4
Chronic multisymptom illness complex in Gulf War I veterans 10 years later.海湾战争一代退伍军人10年后的慢性多症状疾病综合征
Am J Epidemiol. 2006 Jan 1;163(1):66-75. doi: 10.1093/aje/kwj008. Epub 2005 Nov 17.
5
Unexplained illness among Persian Gulf War veterans in an Air National Guard Unit: preliminary report--August 1990-March 1995.国民警卫队空军部队中波斯湾战争退伍军人的不明病因疾病:初步报告——1990年8月至1995年3月
MMWR Morb Mortal Wkly Rep. 1995 Jun 16;44(23):443-7.
6
[Health status after serving in the Gulf war area. The Danish Gulf War Study].[在海湾战争地区服役后的健康状况。丹麦海湾战争研究]
Ugeskr Laeger. 1999 Sep 27;161(39):5423-8.
7
Neurobehavioral deficits in Persian Gulf veterans: additional evidence from a population-based study.海湾战争退伍军人的神经行为缺陷:一项基于人群研究的更多证据。
Environ Res. 2001 Jan;85(1):1-13. doi: 10.1006/enrs.2000.4100.
8
The health of Australian veterans of the 1991 Gulf War: factor analysis of self-reported symptoms.1991年海湾战争澳大利亚退伍军人的健康状况:自我报告症状的因素分析
Occup Environ Med. 2004 Dec;61(12):1014-20. doi: 10.1136/oem.2003.011791.
9
Anthrax vaccination and self-reported symptoms, functional status, and medical conditions in the National Health Survey of Gulf War Era Veterans and Their Families.海湾战争时期退伍军人及其家属全国健康调查中的炭疽疫苗接种与自我报告的症状、功能状况及医疗状况
Ann Epidemiol. 2004 Feb;14(2):81-8. doi: 10.1016/S1047-2797(03)00124-8.
10
Health consequences of the first Persian Gulf War on French troops.第一次海湾战争对法国军队的健康影响。
Int J Epidemiol. 2006 Apr;35(2):479-87. doi: 10.1093/ije/dyi318. Epub 2006 Jan 24.

引用本文的文献

1
Upper gastrointestinal symptoms and Gulf War Illness in a clinical cohort of US veterans: a retrospective, cross-sectional study.美国退伍军人临床队列中的上消化道症状与海湾战争综合征:一项回顾性横断面研究。
BMJ Open Gastroenterol. 2025 Sep 5;12(1):e001859. doi: 10.1136/bmjgast-2025-001859.
2
Crisis in the gut: navigating gastrointestinal challenges in Gulf War Illness with bioengineering.肠道危机:生物工程应对海湾战争病的胃肠道挑战
Mil Med Res. 2024 Jul 8;11(1):45. doi: 10.1186/s40779-024-00547-2.
3
Onset of Irritable Bowel Syndrome, Dyspepsia, Diarrhea, Bloating, and Constipation in Deployed Gulf War Veterans.
海湾战争退伍军人中肠易激综合征、消化不良、腹泻、腹胀和便秘的发病情况
Int J Gasteroenterol (N Y). 2024 Jun;8(1):5-10. doi: 10.11648/ijg.20240801.12. Epub 2024 Feb 5.
4
Dysbiosis in gastrointestinal pathophysiology: Role of the gut microbiome in Gulf War Illness.胃肠道病理生理学中的失调:肠道微生物组在海湾战争综合征中的作用。
J Cell Mol Med. 2023 Apr;27(7):891-905. doi: 10.1111/jcmm.17631. Epub 2023 Jan 30.
5
Pyridostigmine bromide exposure creates chronic, underlying neuroimmune disruption in the gastrointestinal tract and brain that alters responses to palmitoylethanolamide in a mouse model of Gulf War Illness.溴化吡斯的明暴露会在胃肠道和大脑中造成慢性潜在的神经免疫紊乱,改变了在海湾战争病小鼠模型中对棕榈酸乙醇酰胺的反应。
Neuropharmacology. 2020 Nov 15;179:108264. doi: 10.1016/j.neuropharm.2020.108264. Epub 2020 Aug 3.
6
Gastrointestinal neuroimmune disruption in a mouse model of Gulf War illness.海湾战争病小鼠模型中的胃肠道神经免疫紊乱。
FASEB J. 2019 May;33(5):6168-6184. doi: 10.1096/fj.201802572R. Epub 2019 Feb 21.
7
Intestinal Hyperpermeability in Gulf War Veterans With Chronic Gastrointestinal Symptoms.患有慢性胃肠道症状的海湾战争老兵的肠道通透性增加。
J Clin Gastroenterol. 2019 Aug;53(7):e298-e302. doi: 10.1097/MCG.0000000000001135.
8
Evidence for Somatic Hypersensitivity in Veterans With Gulf War Illness and Gastrointestinal Symptoms.患有海湾战争病和胃肠道症状的退伍军人存在躯体敏感性的证据。
Clin J Pain. 2018 Oct;34(10):944-949. doi: 10.1097/AJP.0000000000000611.
9
Meta-analysis of self-reported health symptoms in 1990-1991 Gulf War and Gulf War-era veterans.1990 - 1991年海湾战争及海湾战争时期退伍军人自我报告健康症状的荟萃分析。
BMJ Open. 2018 Feb 13;8(2):e016086. doi: 10.1136/bmjopen-2017-016086.
10
Infectious Gastroenteritis as a Risk Factor for Tropical Sprue and Malabsorption: A Case-Control Study.感染性肠胃炎作为热带口炎性腹泻和吸收不良的危险因素:一项病例对照研究。
Dig Dis Sci. 2015 Nov;60(11):3379-85. doi: 10.1007/s10620-015-3768-8. Epub 2015 Jun 27.