Stefanidou M, Koutselinis A, Pappas F, Methenitou G
Department of Forensic Medicine and Toxicology, School of Medicine, Athens, Greece.
Vet Hum Toxicol. 1996 Dec;38(6):420-2.
Insect acetylcholinesterase has received special attention following the discovery that inhibition of the enzyme is the mechanism of activity of the organophosphate and carbamate insecticides. Apiculture is an important source of Greek income and as the detection of anticholinesterase insecticides in bees is very difficult, investigation of the cause of death of honeybees due to acetylcholinesterase inhibition is of great value and will contribute to the differential diagnosis of bee diseases. The enzymatic assay is not capable of distinguishing between individual pesticides', but is an indicator of the exposure of bees to anticholinesterase insecticides.
自从发现抑制昆虫乙酰胆碱酯酶是有机磷和氨基甲酸酯类杀虫剂的作用机制后,昆虫乙酰胆碱酯酶就受到了特别关注。养蜂业是希腊收入的一个重要来源,由于很难检测蜜蜂体内的抗胆碱酯酶杀虫剂,因此研究蜜蜂因乙酰胆碱酯酶抑制而死亡的原因具有重要价值,将有助于蜜蜂疾病的鉴别诊断。酶活性测定无法区分个别杀虫剂,但可作为蜜蜂接触抗胆碱酯酶杀虫剂的一个指标。