Ancona E, Costantini M, Zaninotto G, Rossi M, Anselmino M, Boccù C, Merigliano S
Istituto di Chirurgia Generale II, Università degli Studi di Padova.
Ann Ital Chir. 1995 Sep-Oct;66(5):597-605.
Recently, it has been demonstrated that the surgical treatment of gastro-esophageal reflux disease is superior to the medical treatment. Further, the surgical treatment gained new popularity because of the introduction and diffusion of laparoscopic techniques. A careful definition of gastro-esophageal reflux disease, based on the underlying pathophysiological abnormality (i.e.: an increased exposure of the distal esophagus to the refluxed acid juice), and a proper selection of patients candidate to surgery must however be maintained, together with a proper surgical technique, in order to achieve satisfactory results. In this paper, the authors outline in this paper the general principles of anti-reflux surgery and review the most recent results obtained with Nissen fundoplication as well as with other antireflux procedures. They describe in detail the surgical technique of the Nissen fundoplication ("Floppy" Nissen) by a laparoscopic approach. They review their experience in this with 15 operations performed since June 1992, and report the results of an Italian multicentric survey study on laparoscopic surgery for gastro-esophageal reflux disease. Recent series appeared in Literature are also reviewed. In conclusion, the authors underline the need for careful prospective studies and long-term clinical and functional follow-up of patients undergoing laparoscopic anti-reflux surgery before drawing definitive conclusions on its efficacy. However, early results seem to be really promising.
最近,已经证明胃食管反流病的手术治疗优于药物治疗。此外,由于腹腔镜技术的引入和推广,手术治疗重新受到欢迎。然而,为了取得满意的效果,必须基于潜在的病理生理异常(即远端食管暴露于反流酸性胃液增加)对胃食管反流病进行精确界定,正确选择手术候选患者,并采用恰当的手术技术。在本文中,作者概述了抗反流手术的一般原则,并回顾了nissen胃底折叠术以及其他抗反流手术取得的最新成果。他们详细描述了通过腹腔镜途径进行nissen胃底折叠术(“松弛型”nissen)的手术技术。他们回顾了自1992年6月以来进行的15例此类手术的经验,并报告了一项关于胃食管反流病腹腔镜手术的意大利多中心调查研究结果。还对文献中最近出现的系列研究进行了回顾。总之,作者强调在对腹腔镜抗反流手术的疗效得出明确结论之前,需要对接受该手术的患者进行仔细的前瞻性研究以及长期的临床和功能随访。然而,早期结果似乎确实很有前景。