Owens C M, Allan R, Thomas K, Evans J, Stevens J
Department of Diagnostic Radiology, St Mary's Hospital and Medical School, London, UK.
Br J Radiol. 1996 Aug;69(824):777-82. doi: 10.1259/0007-1285-69-824-777.
Anonymous antenatal and newborn screening demonstrates a positive HIV seroprevalence of one in 400 in areas of inner city London. European Collaborative Study data show a vertical transmission rate of 15% and suggests that 23% of infected children will develop clinical manifestations of AIDS before reaching 1 year of age [1], meaning that recognition of the radiological findings in vertically-acquired HIV is important. 75 serial cases of vertically-acquired HIV (age range 6 weeks to 12 years, mean age 35 months) presenting to a national referral centre over 48 months were reviewed; the radiographic findings we describe constitute a core of typical abnormalities together with a selection of the rarer manifestations of vertically-acquired HIV.
匿名产前和新生儿筛查显示,伦敦市中心地区的HIV血清阳性率为400分之一。欧洲协作研究数据显示垂直传播率为15%,并表明23%的受感染儿童在1岁之前会出现艾滋病临床表现[1],这意味着识别垂直感染HIV的影像学表现很重要。我们回顾了48个月内到一家国家转诊中心就诊的75例垂直感染HIV的连续病例(年龄范围6周至12岁,平均年龄35个月);我们所描述的影像学表现构成了典型异常的核心,以及一些垂直感染HIV的罕见表现。