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卵黄样黄斑变性和贝斯特黄斑变性是同一种疾病(作者译)

[Vitelline macular degeneration and Best's macular degeneration are the same disease (author's transl)].

作者信息

Jaeger W, Bischoff E

出版信息

Klin Monbl Augenheilkd. 1977 Jun;170(6):890-9.

PMID:894995
Abstract

In 1905 F. Best had discovered infantile macular degeneration with dominant transmission, later named after him. From Best's pedigree 19 members could be examined by us. Besides the usual examination-methods, EOG, ERG, Fluorescein-Angiography and Chromato-Ophthalmoscopy were applied. In this way the characteristic findings of vitelline macular degeneration could be demonstrated. 7 family-members were typically affected according to their ages. 2 of them were found to be carriers with normal macula; they had however a pathological EOG. The question, if the diagnosis of Best's macular degeneration should be used further in the system of the hereditary macular degenerations or whether it is indeed the same disease as vitelline macular degeneration, is discussed. Best's macular degeneration and vitelline macular degeneration are synonymous. We recommend, that the term vitelline macular degeneration ought to be used intead of Best's macular degeneration. It remains F. Best's merit, that this disease has been recognised and des

摘要

1905年,F. 贝斯特发现了具有显性遗传的婴儿黄斑变性,后来该病以他的名字命名。我们对贝斯特家族谱系中的19名成员进行了检查。除了常规检查方法外,还应用了眼电图(EOG)、视网膜电图(ERG)、荧光素血管造影和彩色眼底镜检查。通过这种方式,可以证实卵黄样黄斑变性的特征性表现。7名家族成员根据其年龄表现出典型症状。其中2人被发现是黄斑正常的携带者;然而,他们的眼电图检查结果异常。文中讨论了在遗传性黄斑变性系统中是否应进一步使用贝斯特黄斑变性的诊断,或者它是否确实与卵黄样黄斑变性为同一种疾病。贝斯特黄斑变性和卵黄样黄斑变性是同义词。我们建议,应使用卵黄样黄斑变性这一术语,而非贝斯特黄斑变性。F. 贝斯特的功绩在于他识别出了这种疾病并……(原文此处似乎不完整)

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