Samlali R, Acharki A, Sahraoui S, Tihyfa M, Benider A, Kahlain A
Centre d'oncologie, CHU Ibn Rochd, Casablanca, Maroc.
Bull Cancer. 1996 Oct;83(10):882-5.
Leiomyosarcoma of the larynx is extremely rare, only 21 cases were reported in the literature. The authors report a personal case in a 26 years old patient treated by a total laryngectomy and analyse all cases of the literature. It comes in relative young man (42 years old) in regard to the others ORL localisations. There is not tobacco relation. The lymph node extension is rare however the distant metastasis are frequent specially in lung. The treatment is based on surgery, the neck lymphadenectomy is possible in patients with cervical lymph nodes. The Leiomyosarcoma is a resistant tumor to the irradiation and chemotherapy however the postoperative irradiation is justified. The prognosis of this tumor is reserved on account of local recurrences and distant metastasis.
喉平滑肌肉瘤极为罕见，文献中仅报道过21例。作者报告了1例26岁患者接受全喉切除术的个人病例，并分析了文献中的所有病例。与其他耳鼻喉局部病变相比，该病患者相对年轻（42岁）。与吸烟无关。淋巴结转移很少见，但远处转移很常见，尤其是肺转移。治疗以手术为主，有颈部淋巴结转移的患者可行颈部淋巴结清扫术。平滑肌肉瘤对放疗和化疗耐药，但术后放疗是合理的。由于局部复发和远处转移，该肿瘤的预后不佳。
