Paczona R, Jóri J, Tiszlavicz L, Czigner J
Department of Otorhinolaryngology, Albert Szent-Györgyi Medical University, Szeged, Hungary.
Ann Otol Rhinol Laryngol. 1999 Jul;108(7 Pt 1):677-82. doi: 10.1177/000348949910800711.
Leiomyosarcoma of the larynx is an extremely rare malignancy. Until now, only 35 cases have been reported, and only 19 were reported in English. We present 2 new cases observed in the last 3 years at our department. Correct histologic diagnosis can only be made on immunohistochemical and electron microscopic grounds. A 65-year-old man previously treated for a premalignant vocal cord lesion and a 31-year-old woman who previously underwent operation on a benign vocal cord lesion are presented. Only surgical treatment (total laryngectomy and endolaryngeal laser resection) was performed. Thirty-six and 22 months after the initial surgical intervention, both patients are alive and well, with no evidence of local recurrence or distant metastasis.
喉平滑肌肉瘤是一种极为罕见的恶性肿瘤。截至目前，仅报告了35例，其中仅有19例为英文报道。我们呈现过去3年在我们科室观察到的2例新病例。正确的组织学诊断只能基于免疫组化和电子显微镜检查结果做出。报告了一名曾接受过癌前声带病变治疗的65岁男性，以及一名曾接受过良性声带病变手术的31岁女性。仅进行了手术治疗（全喉切除术和喉内激光切除术）。在初次手术干预后36个月和22个月，两名患者均存活且状况良好，无局部复发或远处转移迹象。
