Gélisse R, Ambrosi P, Stoppa A M, Habib G, Sunda J, Kreitmann B, Métras D, Luccioni R
Service de cardiologie B, hôpital de la Timone, Marseille.
Arch Mal Coeur Vaiss. 1996 Sep;89(9):1205-7.
Lymphoma is a classical complication of cardiac transplantation. The authors report a case in which the disease affected the cardiac graft. There were few symptoms and a good response to treatment was obtained. The patient underwent cardiac transplantation at 48 years of age because of primary dilated cardiomyopathy. Four years later, she presented with general ill health and a left supraclavicular lymphadenopathy which led to the diagnosis of a tumour of the atria extending into the mediastinum. MRI was the investigation which gave the best images of tumour extension. As with most late lymphomas of transplanted patients, the proliferation was a monoclonal B type. A significant reduction of tumour size was observed during the 13 months follow-up with chemotherapy and there were no cardiac functional signs.
淋巴瘤是心脏移植的典型并发症。作者报告了一例该疾病累及心脏移植移植物的病例。症状较少，且治疗反应良好。该患者因原发性扩张型心肌病于48岁时接受了心脏移植。四年后，她出现全身不适和左锁骨上淋巴结肿大，进而诊断为心房肿瘤延伸至纵隔。MRI是显示肿瘤延伸情况最佳的检查方法。与大多数移植患者的晚期淋巴瘤一样，增殖为单克隆B型。在化疗后的13个月随访中观察到肿瘤大小显著缩小，且没有心脏功能异常迹象。
