Mizuno T, Saito M
Département de Biologie, Faculté des Sciences pharmaceutiques, Teikyo Université, Kanagawa-ken, Japan.
C R Seances Soc Biol Fil. 1996;190(4):497-501.
We have studied the prostatic bud induction in the urogenital sinus of androgen-receptor deficient mice, and found that epidermal growth factor (EGF), keratinocyte growth factor (KGF) as well as transforming growth factor-alpha (TGF-alpha) can provoke prostatic bud formation in the androgen-receptor deficient sinus cultured in the medium deprived of androgens.