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[大鼠躯干及选择性胃迷走神经切断术相关的动物实验(作者译)]

[Experiments in animals in connexion with truncal and selective gastric vagotomy in rats (author's transl)].

作者信息

Schwamberger K, Geir W

出版信息

Langenbecks Arch Chir. 1977 Jul 13;344(1):53-60. doi: 10.1007/BF01259353.

DOI:10.1007/BF01259353
PMID:895301
Abstract

The effects of truncal and selective gastric vagotomy after 9 h ligation of the pylorus were studied on Shay rats. No statistically significant difference was found with regard to gastric tonicity, volume of gastric juice, its pH value, nor with regard to the acidity. However, the size of the stress ulcers showed evident differences; vagotomy of the trunk protects the rat better from developing ulcers than selective vagotomy. By means of additional experiments e.g. ligature of the left gastric artery, truncal and selective gastric vagotomy performed simultaneously, we could demonstrate that this statistically significant difference is due to devascularisation of the lesser curvature of the stomach.

摘要

在幽门结扎9小时后,对沙伊大鼠进行了躯干和选择性胃迷走神经切断术的效果研究。在胃张力、胃液量、pH值以及酸度方面未发现统计学上的显著差异。然而,应激性溃疡的大小显示出明显差异;躯干迷走神经切断术比选择性迷走神经切断术能更好地保护大鼠免于发生溃疡。通过额外的实验,例如结扎胃左动脉、同时进行躯干和选择性胃迷走神经切断术,我们能够证明这种统计学上的显著差异是由于胃小弯的血管化缺失所致。

相似文献

1
[Experiments in animals in connexion with truncal and selective gastric vagotomy in rats (author's transl)].[大鼠躯干及选择性胃迷走神经切断术相关的动物实验(作者译)]
Langenbecks Arch Chir. 1977 Jul 13;344(1):53-60. doi: 10.1007/BF01259353.
2
[Incidence of stress ulcer and secretion of gastric juice following truncal and selective vagotomy].
Z Exp Chir. 1976;9(1):47-56.
3
Results of elective duodenal ulcer surgery in women: comparison of truncal vagotomy and antrectomy, gastric selective vagotomy and pyloroplasty, proximal gastric vagotomy.
Ann Surg. 1978 May;187(5):576-82. doi: 10.1097/00000658-197805000-00017.
4
[Experimental animal studies on the significance of endogenous prostaglandins in maintaining the integrity of the stomach mucosa after truncal vagotomy].
Z Exp Chir Transplant Kunstliche Organe. 1988;21(6):322-7.
5
Proximal gastric vagotomy: effects of two operative techniques on clinical and gastric secretory results.近端胃迷走神经切断术:两种手术技术对临床及胃分泌结果的影响。
Ann Surg. 1976 Oct;184(4):435-42. doi: 10.1097/00000658-197610000-00006.
6
Proximal gastric vagotomy compared with vagotomy and antrectomy and selective gastric vagotomy and pyloroplasty.近端胃迷走神经切断术与迷走神经切断术加胃窦切除术、选择性胃迷走神经切断术加幽门成形术的比较。
Ann Surg. 1977 Oct;186(4):510-7. doi: 10.1097/00000658-197710000-00013.
7
The role of endogenous prostaglandins in maintaining the integrity of the gastric mucosa in Shay's ulcer model after truncal vagotomy in rat.
Acta Chir Hung. 1988;29(3):205-13.
8
[Vagotomy in the prevention of ulcer after portocaval anastomosis in rats (author's transl)].[迷走神经切断术对大鼠门腔静脉吻合术后溃疡的预防作用(作者译)]
Dtsch Med Wochenschr. 1974 Sep 20;99(38):1872, 77.
9
Proximal gastric vagotomy and suprapyloric antrectomy. Experimental evaluation in dogs.近端胃迷走神经切断术和幽门上胃窦切除术。犬的实验评估。
Arch Surg. 1979 May;114(5):623-7. doi: 10.1001/archsurg.1979.01370290073015.
10
Fasting and postprandial serum gastrin levels before and after highly selective gastric vagotomy, truncal vagotomy with pyloroplasty and truncal vagotomy with antrectomy: is there a cholinergic antral gastrin inhibitory and releasing mechanism?高选择性胃迷走神经切断术、胃大部切除术加幽门成形术以及胃大部切除术加胃窦切除术前及术后的空腹和餐后血清胃泌素水平:是否存在胆碱能性胃窦胃泌素抑制和释放机制?
Br J Surg. 1978 Nov;65(11):797-800. doi: 10.1002/bjs.1800651110.

本文引用的文献

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Vagotomy in the rat. A study of its effects on stomach and small intestine.大鼠迷走神经切断术。对其对胃和小肠影响的研究。
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6
[Possibilities and effects of gastric selective vagotomy in the rat].[大鼠胃选择性迷走神经切断术的可能性及效果]
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7
The anatomic basis for the vriable adequacy of incomplete vagotomy: I. The various secretory and ulcerogenic potentials of various anatomic types of incomplete vagotomy in Shay rats.不完全迷走神经切断术效果差异的解剖学基础:I. Shay大鼠不同解剖类型不完全迷走神经切断术的各种分泌及致溃疡潜能
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Effect of vagotomy on pancreatic secretion stimulated by endogenous and exogenous secretin.迷走神经切断术对内源性和外源性促胰液素刺激胰腺分泌的影响。
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Experimental gastric ulcer in Shay rat. I. Pathogenesis of Shay ulcer. Effect of ligation time on ulcer incidence, ulcer index and mortality.
Acta Chir Scand Suppl. 1971;418:1-62.
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[Influence of vagus nerve on ulcus formation in portacaval anastomosis of rats].[迷走神经对大鼠门腔静脉吻合术中溃疡形成的影响]
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