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[大鼠躯干及选择性胃迷走神经切断术相关的动物实验(作者译)]

[Experiments in animals in connexion with truncal and selective gastric vagotomy in rats (author's transl)].

作者信息

Schwamberger K, Geir W

出版信息

Langenbecks Arch Chir. 1977 Jul 13;344(1):53-60. doi: 10.1007/BF01259353.

Abstract

The effects of truncal and selective gastric vagotomy after 9 h ligation of the pylorus were studied on Shay rats. No statistically significant difference was found with regard to gastric tonicity, volume of gastric juice, its pH value, nor with regard to the acidity. However, the size of the stress ulcers showed evident differences; vagotomy of the trunk protects the rat better from developing ulcers than selective vagotomy. By means of additional experiments e.g. ligature of the left gastric artery, truncal and selective gastric vagotomy performed simultaneously, we could demonstrate that this statistically significant difference is due to devascularisation of the lesser curvature of the stomach.

摘要

在幽门结扎9小时后,对沙伊大鼠进行了躯干和选择性胃迷走神经切断术的效果研究。在胃张力、胃液量、pH值以及酸度方面未发现统计学上的显著差异。然而,应激性溃疡的大小显示出明显差异;躯干迷走神经切断术比选择性迷走神经切断术能更好地保护大鼠免于发生溃疡。通过额外的实验,例如结扎胃左动脉、同时进行躯干和选择性胃迷走神经切断术,我们能够证明这种统计学上的显著差异是由于胃小弯的血管化缺失所致。

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