Kobayashi A, Maeda K, Fu A, Hamada K, Chou S, Kunimatsu M, Narita N
Second Department of Internal Medicine, Nara Medical University, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1996 Oct;34(10):1130-5.
A 68-year-old woman with bronchial asthma complained of fever, right thigh pain, sensory disturbance at the tips of the upper and lower limbs, and abdominal pain. She had severe eosinophilia and radiologic examination showed a mass-like shadow in the left lower lobe of the lung. Allergic granulomatous angiitis was diagnosed on the basis of findings from a muscle biopsy (gangrenous vasculitis with eosinophilia). This patient also had positive results of serological tests (Ouchterlony method) for various parasite antigens, despite the fact that no eggs of parasites were found in her feces. After steroid administration, the serological reactivity to parasite antigens had decreased. The positive reactions to parasite antigens was probably related to the cause of the vasculitis.
一名68岁的支气管哮喘女性患者，主诉发热、右大腿疼痛、上下肢末端感觉障碍及腹痛。她有严重的嗜酸性粒细胞增多症，放射学检查显示左肺下叶有一个肿块样阴影。根据肌肉活检结果（嗜酸性粒细胞性坏疽性血管炎）诊断为变应性肉芽肿性血管炎。尽管在该患者粪便中未发现寄生虫卵，但她针对各种寄生虫抗原的血清学检测（双向琼脂扩散法）结果呈阳性。给予类固醇治疗后，其对寄生虫抗原的血清学反应性降低。对寄生虫抗原的阳性反应可能与血管炎的病因有关。
