Chiba A, Keshishian H
Department of Cell and Structural Biology, University of Illinois, Urbana, Illinois, 61801, USA.
Dev Biol. 1996 Dec 15;180(2):424-32. doi: 10.1006/dbio.1996.0316.
Neurons contact their neighbors through a diverse array of cell adhesion and other surface molecules. These molecules can exhibit highly regulated patterns of expression, underscoring their multiple roles in establishing specific interactions between neurons and their environment. Recent studies are beginning to ask how these membrane-bound neural recognition molecules interact with each other and intracellular signaling pathways within an individual neuronal growth cone, and direct the formation of neural connections during development.
神经元通过多种细胞黏附分子和其他表面分子与相邻神经元进行接触。这些分子可呈现出高度受调控的表达模式，突显了它们在神经元与其周围环境建立特定相互作用过程中的多种作用。最近的研究开始探讨这些膜结合神经识别分子如何在单个神经元生长锥内相互作用以及与细胞内信号通路相互作用，并在发育过程中指导神经连接的形成。
