细菌转铁蛋白和乳铁蛋白受体蛋白基因的快速鉴定与克隆
Rapid identification and cloning of bacterial transferrin and lactoferrin receptor protein genes.
作者信息
Ogunnariwo J A, Schryvers A B
机构信息
Department of Microbiology and Infectious Diseases, University of Calgary, Alberta, Canada.
出版信息
J Bacteriol. 1996 Dec;178(24):7326-8. doi: 10.1128/jb.178.24.7326-7328.1996.
Abstract
The sequences of genes encoding the transferrin and lactoferrin receptor proteins from several bacterial species were analyzed for areas of identity in the predicted protein sequences. Degenerate oligonucleotide primers were designed and tested for their ability to amplify portions of the receptor genes. Primer pairs capable of amplifying products of the tbpA/lbpA or tbpB/lbpB genes from all species possessing these receptors were identified.
摘要
对几种细菌物种中编码转铁蛋白和乳铁蛋白受体蛋白的基因序列进行了分析，以寻找预测蛋白质序列中的相同区域。设计了简并寡核苷酸引物，并测试了它们扩增受体基因部分序列的能力。鉴定出了能够从所有拥有这些受体的物种中扩增出tbpA/lbpA或tbpB/lbpB基因产物的引物对。
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