Pigatto P D, Legori A, Bigardi A S, Guarrera M, Tosti A, Santucci B, Monfrecola G, Schena D
Department of Dermatology, University of Milan, Italy.
Am J Contact Dermat. 1996 Sep;7(3):158-63.
A total of 1,050 patients with histories and clinical pictures suggestive of photoallergic contact dermatitis were seen. All the patients underwent photopatch tests with haptens proposed by the Gruppo Italiano Ricerca Dermatiti da Contatto plus other substances suggested by each patient's history. Two hundred fifty-nine patients (24.6%) were positive to at least one test substance of the standard series or to substances added. Typical photoallergic reactions were seen in 198 subjects (259 minus 40 toxic photodermatitis to chlorpromazine and 21 to promethazine), which represents 18.8% of the total population. Topical drugs represent the most involved substances in photodermatitis. The incidence in our population was about equal for antimicrobial agents, additives to fragrances, and fragrances themselves. Other allergens found were salicylanilides, whereas sun-screening agents were the fifth group of haptens but with clear-cut relevance. This study is a first attempt to organize the data about results of photopatch tests applied to Italian patients.
共诊治了1050例有光变应性接触性皮炎病史及临床表现的患者。所有患者均接受了由意大利接触性皮炎研究小组推荐的变应原以及根据每位患者病史所建议的其他物质进行的光斑贴试验。259例患者（24.6%）对标准系列中的至少一种试验物质或添加物质呈阳性反应。198名受试者出现典型的光变应性反应（259例减去对氯丙嗪的40例中毒性光性皮炎和对异丙嗪的21例），占总人数的18.8%。局部用药是光性皮炎中最常涉及的物质。在我们的研究人群中，抗菌剂、香料添加剂和香料本身的发病率大致相同。发现的其他变应原是水杨酰苯胺，而防晒剂是第五类变应原，但具有明确的相关性。本研究首次尝试整理应用于意大利患者的光斑贴试验结果的数据。
