Vandevelde I L, Duckworth E, Reep R L
Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610, USA.
Anat Embryol (Berl). 1996 Dec;194(6):581-93. doi: 10.1007/BF00187471.
The trajectory of long distance intrahemispheric corticocortical axons has been investigated using the anterograde fluorescent axonal tracer fluororuby. Most axons of this kind were found to travel through the gray matter of layers VI and VII rather than in the white matter. The cell-sparse zone immediately superficial to layer VII contains a dense aggregate of longitudinally directed axons. Corticocortical axons traveling in the mediolateral plane also utilize the deep gray matter predominately. Layer VII neurons are persistent remnants of the subplate in rats. Based on our retrograde labeling results, they are involved in long distance as well as local corticocortical connections. Layer VII neurons are often labeled in a more continuous pattern after cortical injections of retrograde tracers than neurons of layers II, III and V, which are labeled in a patchy manner.
利用顺行荧光轴突示踪剂荧光红宝石对长距离半球内皮质-皮质轴突的轨迹进行了研究。发现这类轴突大多穿过VI层和VII层的灰质，而非白质。紧邻VII层浅面的细胞稀疏区含有密集的纵向轴突束。在内外侧平面走行的皮质-皮质轴突也主要利用深部灰质。VII层神经元是大鼠中板层的残留部分。根据我们的逆行标记结果，它们参与长距离以及局部皮质-皮质连接。与以斑片状方式标记的II、III和V层神经元相比，在皮质注射逆行示踪剂后，VII层神经元常以更连续的模式被标记。
