Mascagni F, McDonald A J, Coleman J R
Department of Cell Biology and Neuroscience, University of South Carolina School of Medicine, Columbia 29208.
Neuroscience. 1993 Dec;57(3):697-715. doi: 10.1016/0306-4522(93)90016-9.
The projections of the rat temporal cortex to the amygdala and cerebral cortex were studied using the sensitive anterograde tracer, Phaseolus vulgaris leucoagglutinin. These studies revealed that the core of temporal area 1 had no projections to the amygdala but did send efferents to several cortical fields that projected to the amygdala, including temporal area 2, temporal area 3, the lateral occipital area 2, and a cortical zone along the dorsal, rostral and caudal borders of temporal area 1 ("Tel fringe"). The temporal area 1 fringe cortex had light projections to the amygdala that were confined to the dorsolateral subdivision of the lateral amygdaloid nucleus. Temporal area 2 and the caudal portion of temporal area 3 had projections to both the dorsolateral and ventromedial subdivisions of the lateral nucleus; the projection from temporal area 2 targeted mainly the ventromedial subdivision, whereas the projection from the caudal portion of temporal area 3 terminated primarily in the dorsolateral subdivision. The rostral portion of temporal area 3 had projections to both subdivisions of the lateral nucleus and to the basal magnocellular nucleus. Temporal areas 2 and 3 also had light projections to the lateral capsular subdivision of the central amygdaloid nucleus. Temporal cortical areas exhibited extensive reciprocal connections with each other. Temporal areas with amygdaloid projections also had extensive projections to the perirhinal cortex. The results of the present investigation, in conjunction with other studies of temporal cortical connections, suggest that all temporal regions projecting to the amygdala are multimodal sensory areas. The core of temporal area 1, which is probably the primary auditory area, apparently has no direct projections to the amygdala. The differential projections of different temporal areas to the amygdala suggests the existence of several distinct multimodal pathways arranged in a parallel configuration.
使用敏感的顺行示踪剂菜豆白细胞凝集素，对大鼠颞叶皮质向杏仁核和大脑皮质的投射进行了研究。这些研究表明，颞叶1区的核心没有向杏仁核的投射，但确实向几个投射到杏仁核的皮质区域发出了传出纤维，包括颞叶2区、颞叶3区、枕外侧2区以及沿着颞叶1区背侧、吻侧和尾侧边界的一个皮质区（“颞叶边缘区”）。颞叶1区边缘皮质对杏仁核有少量投射，且局限于外侧杏仁核的背外侧亚核。颞叶2区和颞叶3区的尾侧部分向外侧核的背外侧和腹内侧亚核都有投射；来自颞叶2区的投射主要靶向腹内侧亚核，而来自颞叶3区尾侧部分的投射主要终止于背外侧亚核。颞叶3区的吻侧部分向外侧核的两个亚核以及基底大细胞核都有投射。颞叶2区和3区对中央杏仁核的外侧囊亚核也有少量投射。颞叶皮质区域之间表现出广泛的相互连接。有杏仁核投射的颞叶区域对梨状周皮质也有广泛投射。本研究结果与其他关于颞叶皮质连接的研究相结合，表明所有投射到杏仁核的颞叶区域都是多模式感觉区。颞叶1区的核心可能是初级听觉区，显然没有直接向杏仁核的投射。不同颞叶区域向杏仁核的差异投射表明存在几种以平行配置排列的不同多模式通路。
