Penagos H, Jimenez V, Fallas V, O'Malley M, Maibach H I
Occupational Dermatology Service, Social Security Hospital, Panama.
Contact Dermatitis. 1996 Oct;35(4):214-8. doi: 10.1111/j.1600-0536.1996.tb02360.x.
We studied 39 patients with erythema-dyschromicum-perstans-like dermatitis seen at Changuinola Hospital in Panama. They were compared with 41 controls. The 2 groups were native field workers of the banana plantations exposed to many pesticides. In 34 patients, there was a positive patch test reaction to 2,4,5,6-1,3-tetrachloroisophthalonilnitrile (chlorothalonil, TCPN) 0.001% in acetone. In 39 cases, biopsies showed a lichenoid tissue reaction compatible with a chronic pigmented dermatitis or erythema-dyschromicum-perstans-like dermatitis. Chlorothalonil is possibly the cause of the pigmented dermatitis observed in the 39 banana farm workers studied. Until additional studies are carried out, we consider this a possible rather than definite cause-and-effect relationship.
我们研究了在巴拿马的尚吉诺拉医院就诊的39例类持久性色素异常性红斑性皮炎患者。将他们与41名对照者进行比较。这两组均为香蕉种植园的本地田间工人，接触多种农药。34例患者对丙酮中0.001%的2,4,5,6-1,3-四氯异酞腈（百菌清，TCPN）斑贴试验呈阳性反应。39例活检显示苔藓样组织反应，符合慢性色素性皮炎或类持久性色素异常性红斑性皮炎。百菌清可能是所研究的39名香蕉农场工人中观察到的色素性皮炎的病因。在进行更多研究之前，我们认为这是一种可能而非确定的因果关系。
