简短通讯：栓塞治疗在肝细胞癌骨转移疼痛中的价值；与放射治疗的对比研究

Short communication: the value of embolization therapy in painful osseous metastases from hepatocellular carcinomas; comparative study with radiation therapy.

作者信息

Murakami R, Baba Y, Furusawa M, Yokoyama T, Nishimura R, Uozumi H, Hatanaka Y, Yamashita Y, Takahashi M

机构信息

Department of Radiology, Kumamoto University School of Medicine, Japan.

出版信息

Br J Radiol. 1996 Nov;69(827):1042-4. doi: 10.1259/0007-1285-69-827-1042.

DOI:10.1259/0007-1285-69-827-1042

PMID:8958023

Abstract

We evaluated the therapeutic effect of transcatheter arterial embolization therapy (TAE) for painful osseous metastases from hepatocellular carcinoma (HCC) in comparison with radiation therapy (RT). TAE using gelatin sponge particles was performed for seven lesions in seven patients. Selective catheterization and embolization were successfully performed in all lesions. Within 10 days after TAE, complete pain relief (CR), partial relief (PR) and no relief (NR) were attained in 57%, 29% and 14%, respectively. RT was used to treat 34 lesions in 22 patients. The dose fractionation schedules were in the range 28.0-50.4 Gy, with 1.8-4.0 Gy per fraction. CR, PR and NR were attained in 47%, 47% and 6%, respectively. There were no serious complications related to these treatments. Both TAE and RT are effective and the treatment of choice should be selected on an individual basis.

摘要

我们比较了经导管动脉栓塞治疗（TAE）与放射治疗（RT）对肝细胞癌（HCC）引起的疼痛性骨转移的治疗效果。对7例患者的7个病灶进行了使用明胶海绵颗粒的TAE治疗。所有病灶均成功进行了选择性插管和栓塞。TAE后10天内，完全缓解（CR）、部分缓解（PR）和未缓解（NR）的比例分别为57%、29%和14%。RT用于治疗22例患者的34个病灶。剂量分割方案在28.0 - 50.4 Gy范围内，每次分割剂量为1.8 - 4.0 Gy。CR、PR和NR的比例分别为47%、47%和6%。这些治疗均未出现严重并发症。TAE和RT均有效，应根据个体情况选择治疗方案。