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左心室功能不全患者的右心室功能:冠状动脉搭桥手术患者的研究

[Right ventricular function in patients with poor left ventricular function: studies in patients undergoing coronary artery bypass surgery].

作者信息

Konishi Y, Matsumoto M, Miwa S, Minakata K

机构信息

Cardiovascular Surgery, Japan Red Cross Society, Wakayama Medical Center, Japan.

出版信息

Kyobu Geka. 1996 Dec;49(13):1074-7.

PMID:8958680
Abstract

In many patients, right ventricular (RV) dysfunction is due to RV infarction. In some patients, however, RV dysfunction may be secondary to the left ventricular (LV) dysfunction. In order to clarify the influence of poor LV function on RV function, RV ejection fraction (EF) was evaluated serially by thermodilution techniques (REF-1, Edwards Laboratories) in patients with LVEF less than 40% who underwent aorto-coronary bypass surgery with uneventful postoperative course. The patients were divided into four groups depending on the site of LV infarction; anterior (n = 13), inferior (n = 8), anterior + inferior (n = 16), and no infarction (n = 4). Control (n = 11) consisted of the patients with LVEF more than 60% and with no significant stenosis of the right coronary artery. Cardiac index, intracardiac pressures and amount of catecholamine used during postoperative course showed no significant differences among the groups including control. However, the groups except for the group of anterior infarction showed significantly low pre- and postoperative RVEF compared with control. Only the group of anterior infarction had almost normal RVEF. These results mean that RV dysfunction associated with inferior infarction remain long afterwards and that low LVEF due to anterior infarction caused little effect on RV function.

摘要

在许多患者中,右心室(RV)功能障碍是由RV梗死引起的。然而,在一些患者中,RV功能障碍可能继发于左心室(LV)功能障碍。为了阐明LV功能不良对RV功能的影响,对左心室射血分数(LVEF)低于40%且接受主动脉冠状动脉搭桥手术且术后过程平稳的患者,采用热稀释技术(REF-1,爱德华兹实验室)连续评估RV射血分数(EF)。根据LV梗死部位将患者分为四组:前壁梗死组(n = 13)、下壁梗死组(n = 8)、前壁+下壁梗死组(n = 16)和无梗死组(n = 4)。对照组(n = 11)由LVEF超过60%且右冠状动脉无明显狭窄的患者组成。术后过程中的心脏指数、心腔内压力和儿茶酚胺用量在包括对照组在内的各组之间无显著差异。然而,除前壁梗死组外,其他组术前和术后的RVEF与对照组相比均显著降低。只有前壁梗死组的RVEF几乎正常。这些结果表明,与下壁梗死相关的RV功能障碍会长期存在,而前壁梗死导致的低LVEF对RV功能影响较小。

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