英国九岁儿童中按种族和哮喘患病情况划分的运动诱发性支气管收缩
Exercise-induced bronchoconstriction by ethnicity and presence of asthma in British nine year olds.
作者信息
Jones C O, Qureshi S, Rona R J, Chinn S
机构信息
Department of Public Health Medicine, St Thomas' Hospital, London, UK.
出版信息
Thorax. 1996 Nov;51(11):1134-6. doi: 10.1136/thx.51.11.1134.
BACKGROUND
The prevalence of exercise-induced bronchoconstriction among British children by ethnicity has not been studied.
METHODS
Peak expiratory flow rate (PEFR) was measured before and after an exercise challenge test using a cycle ergometer in 593 nine year olds from Scottish and inner city English schools. Logistic regression analysis was carried out to assess the association between changes in PEFR with exercise by reported asthma, ethnicity, and sex.
RESULTS
The probability of exercise-induced bronchoconstriction was greater among the asthmatics than in either the children without asthma attacks or wheeze, or in the children with only wheeze (p < 0.01). Asian children were 3.6 times more likely to have exercise-induced bronchoconstriction than white inner city children, and also were more likely to have exercise-induced bronchoconstriction than those from the other ethnic groups (p < 0.01).
CONCLUSION
Exercise challenge can assess the prevalence of asthma in the community and detect under-reporting of asthma in ethnic minorities.
背景
尚未对英国不同种族儿童运动诱发支气管收缩的患病率进行研究。
方法
在来自苏格兰和英格兰市中心学校的593名9岁儿童中，使用自行车测力计在运动激发试验前后测量呼气峰值流速（PEFR）。进行逻辑回归分析以评估报告的哮喘、种族和性别与运动时PEFR变化之间的关联。
结果
哮喘患者发生运动诱发支气管收缩的可能性高于既无哮喘发作也无喘息的儿童，或仅患有喘息的儿童（p < 0.01）。亚裔儿童发生运动诱发支气管收缩的可能性是市中心白人儿童的3.6倍，且比亚裔以外其他种族的儿童更易发生运动诱发支气管收缩（p < 0.01）。
结论
运动激发试验可评估社区中哮喘的患病率，并发现少数族裔哮喘报告不足的情况。
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