McLelland J, Griffin S M
Dermatology Department, Royal Victoria Infirmary, Newcastle upon Tyne, UK.
Clin Exp Dermatol. 1996 Jul;21(4):318-9. doi: 10.1111/j.1365-2230.1996.tb00108.x.
We report a case of metastatic Crohn's disease of the umbilicus which responded to topical corticosteroid treatment. Crohn's disease is a granulomatous disease of the bowel which may affect other organs. The skin is commonly involved, and the cutaneous manifestations may be non-specific, e.g. pyoderma gangrenosum or erythema nodosum, or specific with epithelioid granulomas and multinucleated giant cells in the skin. Specific skin lesions may be contiguous with the bowel at sites including the perineum, mouth and adjacent to fistulae, or separated from it by normal skin from the bowel, a rare condition which has been termed 'metastatic' Crohn's disease.
我们报告一例脐部转移性克罗恩病，经局部皮质类固醇治疗后有反应。克罗恩病是一种肠道肉芽肿性疾病，可累及其他器官。皮肤常受累，皮肤表现可能是非特异性的，如坏疽性脓皮病或结节性红斑，或特异性的，表现为皮肤出现上皮样肉芽肿和多核巨细胞。特异性皮肤病变可能在包括会阴、口腔和瘘管附近等部位与肠道相连，或与肠道被正常皮肤隔开，这种罕见情况被称为“转移性”克罗恩病。
