Valzelli L, Bernasconi S, Cusumano G
Neuropsychobiology. 1977;3(2-3):135-43. doi: 10.1159/000117598.
Prolonged isolation in mice is known to induce several behavioral changes, among which impairment of learning was also reported. On the other hand, alcohol is known to have either stimulant or depressant effects on behavior. Further, alcohol effect is also known to depend on strain-linked characteristics and on emotional ground of animals. Since prolonged isolation may differently change the emotional setting of mice, according to the strain, the behavioral effects of alcohol on avoidance learning, have been studied in two strains of male mice differentially housed. Evidences were obtained that ethanol can either improve or worsen learning performances according to the strain and the housing conditions adopted.
众所周知，小鼠长期隔离会引发多种行为变化，其中也有学习能力受损的报道。另一方面，酒精对行为具有兴奋或抑制作用。此外，酒精的作用还取决于动物的品系相关特征和情绪状态。由于长期隔离可能会根据品系不同程度地改变小鼠的情绪状态，因此我们研究了酒精对两种不同饲养方式的雄性小鼠回避学习的行为影响。结果发现，根据所采用的品系和饲养条件，乙醇对学习表现的影响可能是改善也可能是恶化。
