Valzelli L, Bernasconi S
Neuropsychobiology. 1978;4(2):86-92. doi: 10.1159/000117622.
Mice subjected to prolonged socioenvironmental deprivation gradually develop hyperirritability and hyperreactivity to physical stimuli. This heightened neuroexcitability may or may not debouch into aggressiveness according to strain and sex of the animals, and it is accompanied by a reduced sensitivity to CNS depressants. Socioenvironmental deprivation or isolation is shown to decrease the sensitivity either to pentobarbital or to ethanol potentiation of pentobarbital sleeping time in male mice from two different strains.
长期遭受社会环境剥夺的小鼠会逐渐对物理刺激产生过度易怒和过度反应。这种增强的神经兴奋性根据动物的品系和性别可能会或不会发展为攻击性，并且伴随着对中枢神经系统抑制剂的敏感性降低。社会环境剥夺或隔离已被证明会降低来自两种不同品系的雄性小鼠对戊巴比妥或乙醇增强戊巴比妥睡眠时间的敏感性。
