Yusuf Y, Belmonte A H, Tchertkoff V
Department of Pathology, Metropolitan Hospital/New York Medical College, New York 10029, USA.
Acta Cytol. 1996 Nov-Dec;40(6):1313-6. doi: 10.1159/000334028.
Malignant rhabdoid tumor of the kidney in children is considered a distinct entity. Malignant tumors with rhabdoid features in adults in extrarenal locations and in children over the age of 5 years are considered phenotypic variants.
In a case of recurrent transitional cell carcinoma with rhabdoid features of the kidney in an adult, confirmed immunohistochemically and ultrastructurally, fine needle aspiration cytology showed discohesive, large- to medium-sized polygonal cells with eccentric nuclei; prominent nucleoli; abundant, pink cytoplasm; and paranuclear, eosinophilic density, corresponding to cytoplasmic eosinophilic globules seen in the histologic sections and cytoplasmic filamentous inclusions seen ultrastructurally.
The cytologic features of malignant rhabdoid tumors are characteristic.
儿童肾恶性横纹肌样瘤被认为是一种独特的实体。成人肾外部位及5岁以上儿童具有横纹肌样特征的恶性肿瘤被视为表型变异。
一名成年复发性肾移行细胞癌伴横纹肌样特征的患者，经免疫组织化学和超微结构证实，细针穿刺细胞学显示细胞离散，大小为中到大的多边形细胞，核偏位；核仁突出；细胞质丰富、呈粉红色；核旁有嗜酸性密度，对应于组织学切片中所见的细胞质嗜酸性小球及超微结构中所见的细胞质丝状包涵体。
恶性横纹肌样瘤的细胞学特征具有特异性。
