Chłopkiewicz B, Ejchart A, Marczewska J
Drug Institute, Warsaw, Poland.
Acta Pol Pharm. 1995 Jan-Feb;52(1):31-3.
The mutagenic and genotoxic activities of binazine and hydralazine were studied. In the Ames test, both with and without S-9 fraction, hydralazine was mutagenic in strains Salmonella typhimurium TA100 and TA1537, whereas binazine was not mutagenic in these strains. Both drugs were negative in mice micronucleus test.
