Detry J M
Division of Cardiology, Saint-Luc University Hospital, University of Louvain, Brussels, Belgium.
Eur Heart J. 1996 Dec;17 Suppl G:48-52. doi: 10.1093/eurheartj/17.suppl_g.48.
In this review paper on the pathophysiology of myocardial ischaemia, the recent concepts of the ischaemic cascade, as well as the concepts of stunning and hibernating myocardium, are discussed. It is clear that painful ischaemia is the final phenomenon in the ischaemic cascade and that it is preceded by biochemical disturbances, diastolic and systolic dysfunction and electrocardiographic abnormalities. Silent ischaemia remains a difficult research field.
在这篇关于心肌缺血病理生理学的综述文章中,讨论了缺血级联反应的最新概念以及心肌顿抑和心肌冬眠的概念。显然,疼痛性缺血是缺血级联反应中的最终现象,在此之前会出现生化紊乱、舒张和收缩功能障碍以及心电图异常。无症状性缺血仍然是一个难以研究的领域。