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最佳的旋磨钻及辅助球囊尺寸可减少冠状动脉机械旋磨术后靶血管血运重建的需求。

Optimal burr and adjunctive balloon sizing reduces the need for target artery revascularization after coronary mechanical rotational atherectomy.

作者信息

Kaplan B M, Safian R D, Mojares J J, Reddy V M, Gangadharan V, Schreiber T L, Grines C L, O'Neill W W

机构信息

Division of Cardiology, Department of Medicine, William Beaumont Hospital, Royal Oak, Michigan 48073, USA.

出版信息

Am J Cardiol. 1996 Dec 1;78(11):1224-9. doi: 10.1016/s0002-9149(96)00600-5.

Abstract

We analyzed the effect of differing burr and balloon sizes during mechanical rotational atherectomy on the need for target vessel revascularization at 6 months. The ideal burr/artery ratio and adjunctive balloon/artery ratio for optimizing acute luminal results and minimizing restenosis is unknown. Six-month clinical follow-up was obtained in 311 patients (339 lesions) treated with rotational atherectomy from August 1993 to September 1994, to determine whether procedural results or technique were related to the need for target vessel revascularization. Target vessel revascularization, defined as repeat percutaneous intervention or bypass surgery within 6 months after rotational atherectomy, occurred in 19% of patients. Larger burr/artery ratios, defined as the final burr size divided by the reference artery size, were correlated with decreased postatherectomy diameter stenosis (p <0.009) and decreased final diameter stenosis (p <0.03). However, there was no statistical association between postatherectomy or final diameter stenosis with need for revascularization (p = not significant [NS]). The need for revascularization was lowest for burr/artery ratio between 0.6 to 0.85 (15%) versus burr/artery <0.6 or >0.85 (25%) (p <0.04). Postatherectomy, smaller balloon/artery ratios, defined as the final balloon size divided by the reference artery size, were correlated with lower repeat revascularization rates. Balloon/artery ratios <0.95 (target vessel revascularization = 11% vs 25% in balloon/artery >0.95) were associated with the best luminal results and the least risk for clinical restenosis (p <0.006). For rotational atherectomy, despite improvement in acute luminal results with increased burr/artery ratio, the use of a moderate burr/artery ratio correlated with the lowest revascularization rates. There was no correlation between postatherectomy or final diameter stenosis and need for repeat interventions. However, the use of large balloon/artery ratios after rotablator was associated with higher target vessel revascularization rates.

摘要

我们分析了机械旋磨术期间不同的磨头和球囊尺寸对6个月时靶血管血运重建需求的影响。目前尚不清楚优化急性管腔结果并使再狭窄最小化的理想磨头/动脉比值和辅助球囊/动脉比值。对1993年8月至1994年9月期间接受旋磨术治疗的311例患者(339处病变)进行了6个月的临床随访,以确定手术结果或技术是否与靶血管血运重建需求相关。靶血管血运重建定义为旋磨术后6个月内再次进行经皮介入治疗或搭桥手术,19%的患者出现了这种情况。较大的磨头/动脉比值(定义为最终磨头尺寸除以参考动脉尺寸)与旋磨术后直径狭窄程度降低(p<0.009)和最终直径狭窄程度降低(p<0.03)相关。然而,旋磨术后或最终直径狭窄与血运重建需求之间无统计学关联(p=无显著性差异[NS])。磨头/动脉比值在0.6至0.85之间时血运重建需求最低(15%),而磨头/动脉比值<0.6或>0.85时则为25%(p<0.04)。旋磨术后,较小的球囊/动脉比值(定义为最终球囊尺寸除以参考动脉尺寸)与较低的再次血运重建率相关。球囊/动脉比值<0.95(靶血管血运重建率=11%,而球囊/动脉比值>0.95时为25%)与最佳管腔结果及临床再狭窄风险最低相关(p<0.006)。对于旋磨术,尽管随着磨头/动脉比值增加急性管腔结果有所改善,但使用中等磨头/动脉比值与最低的血运重建率相关。旋磨术后或最终直径狭窄与再次干预需求之间无相关性。然而,旋磨术后使用较大的球囊/动脉比值与较高的靶血管血运重建率相关。

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