用氧化铝加热甘氨酸形成氨基酸。

Formation of amino acids on heating glycine with alumina.

作者信息

Ivanov C P, Slavcheva N N

出版信息

Orig Life. 1977 Apr;8(1):13-9. doi: 10.1007/BF00930934.

Abstract

The conversion of glycine into amino acids on heating at 240 degrees C with basic manganous carbonate and alumina is investigated. Alanine, alpha-aminobutyric acid, norvaline, norleucine, sarcosine, N-ethylglycine, N-methylalanine, N-ethylalanine, aspartic acid and glutamic acid are identified among the products of the reaction. Paper chromatography, ion-exchange chromatography and nuclear magnetic resonance are used for the analysis. A scheme for the observed transformations is presented and it is suggested that it may have been a pathway for the synthesis of amino acids from glycine under primitive Earth conditions.

摘要

研究了甘氨酸在240摄氏度下与碱性碳酸锰和氧化铝加热反应转化为氨基酸的过程。在反应产物中鉴定出了丙氨酸、α-氨基丁酸、正缬氨酸、正亮氨酸、肌氨酸、N-乙基甘氨酸、N-甲基丙氨酸、N-乙基丙氨酸、天冬氨酸和谷氨酸。采用纸色谱法、离子交换色谱法和核磁共振法进行分析。给出了观察到的转化过程的示意图，并提出这可能是在原始地球条件下由甘氨酸合成氨基酸的一条途径。