Suppr超能文献

[儿童睾丸肿瘤。13年病例回顾]

[Testicular tumors in childhood. Review of cases in the course of 13 years].

作者信息

Jiménez Isabel M A, Gómez Fraile A, Aransay Brantot A, López Vázquez F, Delgado Muños M D, Encinas Goenechea A, Matute de Cárdenas J A, Berchi García F J

机构信息

Sección de Urología Pediátrica, Hospital Doce de Octubre Madrid.

出版信息

Cir Pediatr. 1996 Jan;9(1):13-6.

PMID:8962800
Abstract

Testicular and paratesticular tumors are rare in childhood, representing 1-2 percent of the solid tumors in the pediatric age. In patients under 14 years, the incidence is 0.5-2/100,000. The evolution differs from that of the adult. Since 1981 to 1994 we have treated 14 cases of testicular and paratesticular tumors. Mean age was 2.54 years, the younger patients presenting germinal tumors. The most frequent tumor was the yolk sac tumor (36%), followed by teratoma mature (29%), and Leydig cell tumor, epidermoid cyst, paratesticular fibrous hamartoma, paratesticular neuroblastoma and paratesticular rabdomyosarcoma (7% each). A testicular mass was present in all cases (100%). Testicular ultrasound was used in 100%. In all the patients with malignant tumors a thoraco-abdominal CT scans was done to rule out extension or the tumor, being negative in all cases. Alphafetoprotein were high in all the cases of yolk sac tumor, being within normal range one month after surgery except in one case. In 11 patients an orquiectomy was done through an inguinal approach, and in three cases a simple tumorectomy without orquiectomy. No lymphadenectomy was done. All the malignants neoplasms were stage I tumors, except one yolk sac tumor stage III. Postop chemotherapy was applied in this one and in the embrionary rabdomyosarcoma. There were no recurrences after a follow-up mean time of 3.98.

摘要

睾丸及睾丸旁肿瘤在儿童期较为罕见,占小儿实体肿瘤的1%-2%。在14岁以下患者中,发病率为0.5-2/10万。其病情发展与成人不同。1981年至1994年期间,我们共治疗了14例睾丸及睾丸旁肿瘤。平均年龄为2.54岁,年龄较小的患者多为生殖细胞瘤。最常见的肿瘤是卵黄囊瘤(36%),其次是成熟畸胎瘤(29%),以及Leydig细胞瘤、表皮样囊肿、睾丸旁纤维瘤、睾丸旁神经母细胞瘤和睾丸旁横纹肌肉瘤(各占7%)。所有病例(100%)均有睾丸肿块。100%的病例使用了睾丸超声检查。所有恶性肿瘤患者均进行了胸腹CT扫描以排除肿瘤转移,所有病例结果均为阴性。所有卵黄囊瘤病例的甲胎蛋白均升高,除1例患者外,术后1个月均恢复正常。11例患者通过腹股沟入路进行了睾丸切除术,3例患者进行了单纯肿瘤切除术未行睾丸切除术。未进行淋巴结清扫术。除1例Ⅲ期卵黄囊瘤外,所有恶性肿瘤均为Ⅰ期肿瘤。对该例患者及胚胎性横纹肌肉瘤患者进行了术后化疗。平均随访3.98年无复发。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验