Barr P A, Bailey P E, Sumners J, Cassady G
Pediatrics. 1977 Sep;60(3):282-9.
The relation between directly measured arterial blood pressure and blood volume was studied in 61 sick preterm infants. Mean blood volume (derived from plasma volume [T1824 ten-minute albumin space] and hematocrit value) of 26 hypotensive infants (89.1 +/- 17.26 ml/kg) was not significantly different from that of 35 normotensive, but otherwise comparable, infants (91.4 +/- 14.57 ml/kg). There was no relation between arterial mean blood pressure and blood volume. Twenty-one infants with arterial mean blood pressure less than 30 mm Hg were given 1.0 g/kg of 10% salt-poor albumin. Significant increases in blood pressure occurred but were small in magnitude; more than one half of infants had arterial mean blood pressures persistently less than 30 mm Hg. Arterial/alveolar PO2 ratio decreased significantly with albumin infusion in six infants with hyaline membrane disease not receiving continuous distending-airway pressure, suggesting an association between infused albumin and impaired oxygen exchange.
对61例患病早产儿直接测量的动脉血压与血容量之间的关系进行了研究。26例低血压婴儿的平均血容量（由血浆容量[T1824十分钟白蛋白间隙]和血细胞比容值得出）为89.1±17.26ml/kg，与35例血压正常但其他情况相当的婴儿（91.4±14.57ml/kg）相比，差异无统计学意义。动脉平均血压与血容量之间无相关性。对21例动脉平均血压低于30mmHg的婴儿给予1.0g/kg的10%低钠白蛋白。血压显著升高，但幅度较小；超过一半的婴儿动脉平均血压持续低于30mmHg。在6例未接受持续气道正压通气的透明膜病婴儿中，输注白蛋白后动脉/肺泡氧分压比值显著降低，提示输注白蛋白与氧交换受损之间存在关联。
