Stiebel H, Sela M, Pe'er J
Department of Ophthalmology, Beilinson Med Center, Petah Tiqva, Israel.
Ophthalmic Epidemiol. 1995 Dec;2(3):123-7. doi: 10.3109/09286589509057093.
The frequencies of various indications for enucleations have changed during the past decades. Knowledge of these trends may aid us in assessing the efficacy of early diagnostic techniques and improved modes of treatment. This study was designed to evaluate the indications for enucleations and their changes during a period of thirty years in a major Israeli medical center. We present a retrospective review of 463 enucleations performed between 1960 and 1989 at the Hadassah University Hospital, Jerusalem, Israel, and analyze the changes in the indications for enucleations. In our study, fewer enucleations were performed in the last two decades: 105 in the 1970's and 111 in the 1980's, as opposed to 247 in the 1960's. The incidence of enucleations due to glaucoma and to traumatic complications decreased significantly, from 22.3% in the 1960's to 7.7% glaucoma-related enucleations in the 1970's and 1980's, and 7.2% trauma-associated enucleations in the 1980's as opposed to 11.3% in the 1960's, reflecting improved medical management of these conditions. No significant change was noted in the frequency of enucleations due to inflammation, congenital disease or retinal detachment, nor in the number of malignant melanoma-related enucleations. The number of enucleations due to retinoblastoma rose in our study between 1960 and 1989.
在过去几十年间，眼球摘除术各种适应症的发生频率有所变化。了解这些趋势有助于我们评估早期诊断技术的有效性以及改进治疗方式。本研究旨在评估以色列一家主要医疗中心在三十年期间眼球摘除术的适应症及其变化。我们对1960年至1989年期间在以色列耶路撒冷哈达萨大学医院进行的463例眼球摘除术进行了回顾性研究，并分析了眼球摘除术适应症的变化。在我们的研究中，过去二十年进行的眼球摘除术较少：20世纪70年代为105例，80年代为111例，而60年代为247例。因青光眼和创伤性并发症导致的眼球摘除术发生率显著下降，从60年代的22.3%降至70年代和80年代与青光眼相关的眼球摘除术的7.7%，以及80年代与创伤相关的眼球摘除术的7.2%，而60年代为11.3%，这反映了这些病症医疗管理的改善。因炎症、先天性疾病或视网膜脱离导致的眼球摘除术频率以及与恶性黑色素瘤相关的眼球摘除术数量均未发现显著变化。在我们的研究中，1960年至1989年间因视网膜母细胞瘤导致的眼球摘除术数量有所上升。
