Ishigooka M, Hashimoto T, Hayami S, Suzuki Y, Nakada T, Handa Y
Department of Urology, Yamagata University School of Medicine, Japan.
Spinal Cord. 1996 Jul;34(7):411-5. doi: 10.1038/sc.1996.73.
The present study demonstrates the clinical experience of pelvic floor stimulation using percutaneous implantable electrodes and implantable electrical stimulator for the treatment of reflex urinary incontinence in patients with spinal cord injury. Pelvic floor stimulation was carried out on six paraplegic patients who had urinary incontinence from an overactive bladder. After the percutaneous implantation of a pair of electrodes, chronic stimulation was carried out by employing an implanted receiver or an external pulse regulator. Within 4 to 16 weeks of electrical stimulation urinary incontinence was improved in four of the six patients. In two of these six patients, incontinence was completely abolished subjectively. Urodynamic investigations demonstrated an increased volume at the first unstable contraction (P < 0.01) in all of the patients. Inhibition of detrusor overactivity was obtained from this procedure. The stimulation effect appeared to be constant during chronic stimulation. This new procedure probably provides a stable and reliable stimulation effect for long term treatment, and may be an alternative treatment for previous external electrical pelvic floor stimulation.
本研究展示了使用经皮植入电极和植入式电刺激器进行盆底刺激治疗脊髓损伤患者反射性尿失禁的临床经验。对6例因膀胱过度活动导致尿失禁的截瘫患者进行了盆底刺激。经皮植入一对电极后,通过植入式接收器或外部脉冲调节器进行长期刺激。在电刺激4至16周内,6例患者中有4例尿失禁得到改善。在这6例患者中的2例中,主观上失禁完全消除。尿动力学检查显示所有患者首次不稳定收缩时的容量增加(P<0.01)。通过该程序可抑制逼尿肌过度活动。在长期刺激过程中,刺激效果似乎是恒定的。这种新方法可能为长期治疗提供稳定可靠的刺激效果,并且可能是先前外部电盆底刺激的替代治疗方法。