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多发性硬化症患者神经源性膀胱功能障碍的诊断与治疗

Diagnosis and therapy for neurogenic bladder dysfunctions in multiple sclerosis patients.

作者信息

Del Popolo Giulio, Panariello Giovanni, Del Corso Francesca, De Scisciolo Giuseppe, Lombardi Giuseppe

机构信息

Careggi University Hospital, Largo Palagi 1, 50139, Florence, Italy.

出版信息

Neurol Sci. 2008 Dec;29 Suppl 4:S352-5. doi: 10.1007/s10072-008-1042-y.

DOI:10.1007/s10072-008-1042-y
PMID:19089675
Abstract

Neurogenic lower urinary tract dysfunctions are common in patients with multiple sclerosis and for most of them urinary dysfunction has the most negative impact on their social life. No correlation exists between clinical urinary symptoms and urodynamic patterns. Abnormal urodynamic patterns may be present in asymptomatic patients. Both clinical and urodynamic findings may change during the course of the illness. Early diagnostic approach and scheduled follow-ups are mandatory in order to prevent upper urinary tract complications and improve quality of life (QoL).

摘要

神经源性下尿路功能障碍在多发性硬化症患者中很常见,对大多数患者而言,排尿功能障碍对其社交生活的负面影响最大。临床排尿症状与尿动力学模式之间不存在相关性。无症状患者可能存在异常尿动力学模式。在疾病过程中,临床和尿动力学检查结果都可能发生变化。为预防上尿路并发症并提高生活质量(QoL),早期诊断方法和定期随访是必不可少的。

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2
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Biomedicines. 2022 Nov 22;10(12):3001. doi: 10.3390/biomedicines10123001.
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Clinical Characteristics and Urodynamic Analysis of Urinary Dysfunction in Multiple Sclerosis.多发性硬化症患者排尿功能障碍的临床特征及尿动力学分析
Chin Med J (Engl). 2016 Mar 20;129(6):645-50. doi: 10.4103/0366-6999.177970.
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Overactive bladder symptoms in patients with multiple sclerosis: Frequency, severity, diagnosis and treatment.

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Comparison of pelvic floor muscle training, electromyography biofeedback, and neuromuscular electrical stimulation for bladder dysfunction in people with multiple sclerosis: a randomized pilot study.盆底肌训练、肌电图生物反馈和神经肌肉电刺激对多发性硬化症患者膀胱功能障碍的比较:一项随机试验研究
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Combination of a cholinergic drug and an alpha-blocker is more effective than monotherapy for the treatment of voiding difficulty in patients with underactive detrusor.对于治疗逼尿肌活动低下患者的排尿困难,胆碱能药物与α受体阻滞剂联合使用比单一疗法更有效。
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