Murray M I, Halpern M T, Leppik I E
Battelle, Centers for Public Health Research and Evaluation, Arlington, VA 22201, USA.
Epilepsy Res. 1996 Mar;23(2):139-48. doi: 10.1016/0920-1211(95)00090-9.
A cost of illness of refractory epilepsy was developed based on estimates supplied by an expert panel of physicians and a review of the current literature. The basic elements of model can be divided into two main components: direct and indirect costs. Direct costs include the medical resource utilization patterns associated with epilepsy care while the indirect costs represent lost productivity associated with the disease. The results of the analysis indicate that an estimated 24,578 incident cases of epilepsy incur a total of $318,582,669; while our prevalence estimates indicate that 335,167 individuals incur a total of $3,905,183,463, in a given year. Direct medical costs account for one-third of the total costs while indirect costs constitute the remaining two-thirds.
基于医师专家小组提供的估计数据以及对当前文献的综述，得出了难治性癫痫的疾病成本。该模型的基本要素可分为两个主要部分：直接成本和间接成本。直接成本包括与癫痫治疗相关的医疗资源利用模式，而间接成本则代表与该疾病相关的生产力损失。分析结果表明，在给定年份中，估计有24,578例癫痫新发病例产生的总成本为318,582,669美元；而我们的患病率估计表明，335,167人产生的总成本为3,905,183,463美元。直接医疗成本占总成本的三分之一，而间接成本占其余的三分之二。
