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[单次应激对神经系统兴奋性较高的大鼠染色体畸变的诱导频率]

[Frequency of chromosome aberrations induced by a single exposure to stress in rats selected for excitability of the nervous system].

作者信息

Diuzhiova N A, Bykovskaia N V, Vaĭdo A I, Shiriaeva N V, Lopatina N G, Shvartsman P Ia

出版信息

Genetika. 1996 Jun;32(6):851-3.

PMID:8964472
Abstract

The effect of short-term emotional and algesic stress on chromosomal aberration rate in bone marrow cells was studied in four lines of rats selected for excitability of the nervous system. The exposure induced an increase in chromosomal aberration rate only in highly excitable animals; the effect was classified as a low mutagenic. Possible mechanisms of the effect of stress factors on the chromosomal apparatus of cells are discussed.

摘要

在选择出的四组神经系统兴奋性不同的大鼠中,研究了短期情绪应激和痛觉应激对骨髓细胞染色体畸变率的影响。仅在高度兴奋的动物中,该暴露导致染色体畸变率增加;该效应被归类为低致突变性。文中讨论了应激因素对细胞染色体结构产生影响的可能机制。

相似文献

1
[Frequency of chromosome aberrations induced by a single exposure to stress in rats selected for excitability of the nervous system].[单次应激对神经系统兴奋性较高的大鼠染色体畸变的诱导频率]
Genetika. 1996 Jun;32(6):851-3.
2
[Frequency of chromosome aberrations induced by stress and cyclophosphane in bone marrow cells of rats selected for the threshold of nervous system excitability].
Genetika. 1994 Sep;30(9):1224-8.
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[Effect of emotional stress on the frequency of chromosome aberrations in the bone marrow cells of mice].[情绪应激对小鼠骨髓细胞染色体畸变频率的影响]
Biull Eksp Biol Med. 1980 Jul;89(7):91-2.
4
[Characteristics of heterochromatin of heterophase nuclei from interphase neurons of various brain structures selected for the nervous system excitability].
Zh Vyssh Nerv Deiat Im I P Pavlova. 2001 Jul-Aug;51(4):511-3.
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[Single-strand DNA breaks in brain cells of different rat strains under normal condition and during exposure to stress].
Tsitologiia. 2001;43(3):269-73.
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[The characteristics of the development of learned helplessness in rats selected for the excitability threshold of their nervous systems].[根据神经系统兴奋性阈值选择的大鼠习得性无助发展特征]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1998 Nov-Dec;48(6):1058-64.
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Strain and sex differences in the expression of nociceptive behavior and stress-induced analgesia in rats.大鼠伤害性行为表达及应激诱导镇痛中的品系和性别差异。
Brain Res. 2004 Dec 31;1030(2):277-83. doi: 10.1016/j.brainres.2004.10.016.
8
[Incidence of chromosome aberrations in the bone marrow of monkeys and their progeny after exposure to aflatoxin B1].[黄曲霉毒素B1暴露后猴子及其后代骨髓中染色体畸变的发生率]
Tsitol Genet. 1984 May-Jun;18(3):173-6.
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[Chromosomal disorders in the oocytes of rats after stress exposure in the preovulatory period].[排卵前期应激暴露后大鼠卵母细胞中的染色体异常]
Tsitol Genet. 1990 May-Jun;24(3):37-40.
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[Genetic and seasonal characteristics of the effect of stress on pain sensitivity in mice].[应激对小鼠疼痛敏感性影响的遗传和季节性特征]
Biull Eksp Biol Med. 1986 Jan;101(1):11-3.

引用本文的文献

1
Chromosomal instability and cranial asymmetry in the mole-vole Ellobius talpinus Pallas, 1770 polymorphic for coat coloration.
Dokl Biol Sci. 2006 Sep-Oct;410:403-6. doi: 10.1134/s0012496606050176.
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Proliferative activity and characteristics of the structural-functional organization of the chromosomes in cells of the developing brain, related to the genetically determined excitability of the nervous system in rats.发育中大鼠大脑细胞染色体的增殖活性及结构-功能组织特征,与神经系统的遗传决定兴奋性相关
Neurosci Behav Physiol. 2000 May-Jun;30(3):315-9. doi: 10.1007/BF02471784.