在有或没有Ca++存在的情况下，对DNA与碱性肽结合的圆二色性研究。
A circular dichroism study of DNA-basic peptides associations in the absence or in the presence of Ca++.
作者信息
Lacombe C, Laigle A
出版信息
Nucleic Acids Res. 1977 Jun;4(6):1783-91. doi: 10.1093/nar/4.6.1783.
Abstract
The interaction of DNA with basic peptides (Lys methyl ester*, Lys2, (Lys)2methyl ester) has been studied by circular dichroism. The changes of the DNA CD spectra in the presence of peptides are interpreted as a transconformation from the B form to the C form of DNA. The presence of Ca++ in the mixture induces a supplementary transconformation. These observations suggest Ca++-basic peptides-DNA complexes as a structural model for chromatin.
摘要
通过圆二色性研究了DNA与碱性肽（赖氨酸甲酯*、赖氨酸2、（赖氨酸）2甲酯）的相互作用。在肽存在的情况下DNA圆二色光谱的变化被解释为DNA从B型向C型的转变构象。混合物中Ca++的存在诱导了额外的转变构象。这些观察结果表明Ca++-碱性肽-DNA复合物可作为染色质的结构模型。
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