Effects of hypertension control on stroke incidence and fatality: report from Syst.-China and post-stroke antihypertensive treatment.

Syst. China Trial aimed to determine whether titrated antihypertensive treatment could reduce the risk of stroke incidence and other cardiovascular complications among 2,298 older Chinese patients (> or = 60) with isolated systolic hypertension. The data from 3 years follow-up showed that the blood pressure reduction was 7/2 mmHG more in the active treatment group than in the placebo group. Whether this blood pressure reduction results in a clinically meaningful decrease of cardiovascular complications is still under investigation.