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[睡眠呼吸暂停综合征病程中的睡眠倾向与日间嗜睡]

[Propensity for sleep and diurnal somnolence in the course of sleep apnea syndrome].

作者信息

Krieger J, Zamagni M, Sforza E, Petiau C, Trautmann D

机构信息

Unité des troubles du sommeil, Hôpitaux universitaires de Strasbourg, France.

出版信息

Neurophysiol Clin. 1996;26(3):131-7. doi: 10.1016/0987-7053(96)89623-7.

DOI:10.1016/0987-7053(96)89623-7
PMID:8965779
Abstract

Daytime sleepiness is one of the major symptoms of obstructive sleep apnea. However, its definition raises problems, since it may be based on either subjective feeling (evaluated by means of questionnaires or analog visual scales), physiological drive or need (inferred by a sleep latency) or on the concept of sleep propensity defined as the probability of falling asleep (measured by the occurrence of sleep in various circumstances of daily life). Data from the literature suggest that sleep fragmentation and hypoxemia, both related to sleep apneas, cause daytime sleepiness. Our own data show that sleep propensity in a group of 44 patients with obstructive sleep apnea was correlated with the increase in esophageal pressure swings during obstructive apneas. This result suggests that the increased respiratory effort against occluded upper airways also contributes to daytime sleepiness in patients with obstructive sleep apnea.

摘要

日间嗜睡是阻塞性睡眠呼吸暂停的主要症状之一。然而,其定义存在问题,因为它可能基于主观感受(通过问卷调查或视觉模拟量表评估)、生理驱力或需求(通过睡眠潜伏期推断),或者基于定义为入睡概率的睡眠倾向概念(通过日常生活中各种情况下的入睡情况测量)。文献数据表明,与睡眠呼吸暂停相关的睡眠片段化和低氧血症会导致日间嗜睡。我们自己的数据显示,一组44例阻塞性睡眠呼吸暂停患者的睡眠倾向与阻塞性呼吸暂停期间食管压力波动的增加相关。这一结果表明,对上气道阻塞的呼吸努力增加也导致阻塞性睡眠呼吸暂停患者的日间嗜睡。

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