Rodríguez French A, Suárez M, Cornejo M X, de Iglesias M T, Roldán T
Servicio de Enfermedades Infecciosas en el Hospital Santo Tomás.
Rev Med Panama. 1996 Jan-May;21(1-2):4-10.
The authors examined material from the respiratory tract obtained from 55 patients, with silver Methenamine and Giemsa stains to detect Pneumocystis carinii. Twenty five patients were positive. All had fever and fatigue, 80% had dyspnea, 72% had productive cough, and significant weight loss occurred in 48%. None of the patients had signs of pulmonary consolidation. Chest X-Ray showed diffuse infiltrates in 55.2%. Nodular lesions in both lung fields were present in 6.9%. A local infiltrate was seen in 13.6% and no infiltrates were seen in 10.3%. LDH was elevated in all (ranging from 885 4500 UI), 84% of the patients had a PO2 of 70 mmHg or less. Most of the patients, 80%, responded to therapy with Trimethoprim-Sulfa.
作者检查了55例患者呼吸道获取的材料,用六胺银染色和吉姆萨染色检测卡氏肺孢子虫。25例患者呈阳性。所有患者均有发热和疲劳,80%有呼吸困难,72%有咳痰,48%有明显体重减轻。所有患者均无肺实变体征。胸部X线显示55.2%有弥漫性浸润。双肺野有结节性病变的占6.9%。局部浸润见于13.6%,10.3%未见浸润。所有患者乳酸脱氢酶均升高(范围为885~4500 UI),84%的患者动脉血氧分压为70 mmHg或更低。大多数患者(80%)对甲氧苄啶-磺胺治疗有反应。