Benito M C, Sánchez M L, Alvarez M V, Sánchez P
Servicio de Anestesiología y Reanimación, Hospital General Universitario Gregorio Marañón, Madrid.
Rev Esp Anestesiol Reanim. 1996 Aug-Sep;43(7):258-60.
Antithrombin III (AT III) is a physiological inhibitor of coagulation. AT III deficit, whether congenital or acquired, results in a state of hypercoagulability characterized by recurring instances of venous thrombosis in young people. Although AT III levels normally change little during pregnancy, a deficit can be associated to the appearance of recurring thromboembolism and the need to perform cesarean section increases the risk. We report a cesarean section under general anesthesia in a patient with congenital AT III, reviewing the etiology and pathophysiology of this entity as well as its treatment.
抗凝血酶III（AT III）是一种生理性凝血抑制剂。AT III缺乏，无论是先天性的还是后天获得性的，都会导致高凝状态，其特征是年轻人反复出现静脉血栓形成。虽然AT III水平在妊娠期间通常变化不大，但缺乏可能与反复发生的血栓栓塞有关，而剖宫产的需求会增加风险。我们报告了一例先天性AT III缺乏患者在全身麻醉下进行剖宫产的病例，并回顾了该疾病的病因、病理生理学及其治疗方法。
