果蝇的Y染色体是一条进化而来的超数染色体吗？

Is the Y chromosome of Drosophila an evolved supernumerary chromosome?

作者信息

Hackstein J H, Hochstenbach R, Hauschteck-Jungen E, Beukeboom L W

机构信息

Department of Microbiology and Evolutionary Biology, Faculty of Science, Catholic University of Nijmegen, The Netherlands.

出版信息

Bioessays. 1996 Apr;18(4):317-23. doi: 10.1002/bies.950180410.

DOI:10.1002/bies.950180410

PMID:8967900

Abstract

The Y chromosomes of most Drosophila species are necessary for male fertility but they are not involved in sex determination. They have many puzzling properties that resemble the effects caused by B chromosomes. Classical genetic and molecular studies reveal substantial affinities between Y and B chromosomes and suggest that the Y chromosomes of Drosophila are not degenerated homologues of the X chromosomes, but rather that their Y chromosomes evolved as specialized supernumeraries similar to classical B chromosomes.

摘要

大多数果蝇物种的Y染色体对雄性生育能力是必需的，但它们不参与性别决定。它们具有许多令人困惑的特性，类似于B染色体所产生的效应。经典遗传学和分子研究揭示了Y染色体和B染色体之间存在显著的相似性，并表明果蝇的Y染色体并非X染色体的退化同源物，而是其Y染色体是作为类似于经典B染色体的特殊超数染色体进化而来的。