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重症肌无力:免疫机制与免疫疗法

Myasthenia gravis: immunological mechanisms and immunotherapy.

作者信息

Lewis R A, Selwa J F, Lisak R P

机构信息

Department of Neurology, Wayne State University School of Medicine, Detroit, MI 48201, USA.

出版信息

Ann Neurol. 1995 May;37 Suppl 1:S51-62. doi: 10.1002/ana.410370707.

Abstract

This review of the immunological aspects of myasthenia gravis and the immunotherapy of the disease emphasizes the current state of knowledge of the immunological events at the neuromuscular junction, and the immunoregulatory abnormalities noted in myasthenic patients. The treatment modalities available to the clinician are discussed in an attempt to provide information that will allow for a rational approach to therapy.

摘要

本文对重症肌无力的免疫学方面及该疾病的免疫治疗进行综述,着重阐述了神经肌肉接头处免疫事件的当前知识状态,以及重症肌无力患者中发现的免疫调节异常。文中还讨论了临床医生可采用的治疗方式,旨在提供有助于合理进行治疗的信息。

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