Brody J P, Yager P, Goldstein R E, Austin R H
Center for Bioengineering, University of Washington, Seattle 98195-2141, USA.
Biophys J. 1996 Dec;71(6):3430-41. doi: 10.1016/S0006-3495(96)79538-3.
The shrinking of liquid handling systems to the micron and submicron size range entails moving into the area of small Reynolds numbers. The fluid dynamics in this regime are very different from the macroscale. We present an intuitive explanation of how the different physics of small Reynolds numbers flow, along with microscopic sizes, can influence device design, and give examples from our own work using fluid flow in microfabricated devices designed for biological processing.
将液体处理系统缩小到微米和亚微米尺寸范围,意味着进入小雷诺数领域。该领域的流体动力学与宏观尺度有很大不同。我们直观地解释了小雷诺数流动的不同物理特性以及微观尺寸如何影响设备设计,并给出了我们自己在为生物处理设计的微加工设备中使用流体流动的工作示例。